G-Protein Coupled Receptor 94 (GPR94) Antibody
416€ (200 µl)
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935106861
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name
G-Protein Coupled Receptor 94 (GPR94) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430396
tested applications
P-ELISA, WB, IHC, FCM
Description
GPR94 Antibody is a Goat Polyclonal antibody against GPR94.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G-Protein Coupled Receptor 94 (GPR94) |
| Host | Goat |
| Reactivity | Human, Mouse |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC, FCM |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 7184, 22027, 362862 |
| NCBI Accession | NP_003290.1 |
| Alias | P2RY13,GPR94,G protein-coupled receptor 86,P2Y purinoceptor 13, purinergic receptor P2Y G-protein coupled 13,purinergic receptor P2Y,FKSG77,GPCR1,GPR86,P2Y13,SP174 |
| Background | Antibody anti-P2RY13 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
P2RY13 is a G protein-coupled receptor primarily activated by ADP and related nucleotides. It couples to Gi proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating downstream cellular responses. P2RY13 is expressed in immune cells, liver, and the central nervous system, where it regulates lipid metabolism, immune responses, and energy homeostasis. In the liver, P2RY13 plays a key role in cholesterol metabolism by mediating the uptake of high-density lipoproteins (HDL), contributing to cholesterol homeostasis. In immune cells, P2RY13 regulates chemotaxis, cytokine production, and inflammation. Dysregulation of P2RY13 has been linked to lipid disorders, atherosclerosis, and inflammatory diseases. Its role in immune and metabolic regulation makes P2RY13 a promising therapeutic target for managing hyperlipidemia, atherosclerosis, and chronic inflammatory conditions. Understanding its signaling mechanisms could provide novel therapeutic avenues for metabolic and immune-related diseases.
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