Adhesion G Protein-Coupled Receptor D2 (ADGRD2) Antibody

Name: Adhesion G Protein-Coupled Receptor D2 (ADGRD2) Antibody
Brand: Abbexa
SKU: abx015304
Price: 52 EUR
Availability: OnlineOnly

Este producto es parte de ADGRD - Adhesion G-protein coupled receptor D

Pida mas información

935106861

info@markelab.com

Precio

52€ (10 µg)

Antibody anti-ADGRD2

proveedor

Abbexa

reference

abx015304

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Rabbit polyclonal antibody against GPR144 protein. Immunogen region is N-terminal.

Background

ADGRD2, also referred to as GPR144, is another adhesion GPCR predominantly expressed in the central nervous system and reproductive tissues. Similar to ADGRD1, it contains a GAIN domain responsible for receptor cleavage and activation. ADGRD2 has been implicated in neurodevelopmental processes such as synaptic formation, axonal pathfinding, and neural connectivity. The receptor is also involved in modulating immune responses by interacting with extracellular matrix components and other cell surface proteins. It likely signals through cAMP and calcium-dependent pathways, regulating cellular homeostasis and proliferation. Though less studied compared to ADGRD1, ADGRD2's altered expression has been observed in certain cancers and inflammatory disorders, suggesting its potential role in pathology and as a candidate for targeted drug therapies.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Adhesion G Protein-Coupled Receptor D2 (ADGRD2)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.

recommended dilution

WB: 1/500 - 1/3000, ELISA: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.

size 1

10 µg

size 2

100 µg

size 3

200 µg

size 4

300 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ADGRD2

dry ice

availability

Shipped within 5-10 working days.

alias

ADGRD2,adhesion G protein-coupled receptor D2,adhesion G protein-coupled receptor D2, pseudogene,GPR144,G protein-coupled receptor 144,PGR24

uniprot id

https://www.uniprot.org/uniprotkb/Q7Z7M1

gene id

https://www.ncbi.nlm.nih.gov/gene/347088

note

Concentration: 1 mg/ml -

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