Free Fatty Acid Receptor 4 (FFAR4) Antibody
221€ (50 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Free Fatty Acid Receptor 4 (FFAR4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx328170
tested applications
ELISA, WB, IF/ICC
Description
FFAR4 Antibody is a Rabbit Polyclonal against FFAR4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Free Fatty Acid Receptor 4 (FFAR4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/5000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5NUL3 |
| Gene ID | 338557 |
| Alias | FFAR4,PGR4,GPR120,GPR129,G-protein-coupled receptor GT01,GT01,G protein-coupled receptor 120,G protein-coupled receptor 129,omega-3 fatty acid receptor 1,O3FAR1,G-protein coupled receptor GT01,OB10Q,BMIQ10 |
| Background | Antibody anti-FFAR4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
FFAR4, also known as GPR120, is a G protein-coupled receptor activated by long-chain free fatty acids, including omega-3 fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). FFAR4 is expressed in adipocytes, macrophages, and the gastrointestinal tract, where it regulates metabolism, inflammation, and insulin sensitivity. In adipose tissue, FFAR4 activation enhances insulin sensitivity and glucose uptake, while in macrophages, it suppresses pro-inflammatory signaling pathways, such as NF-κB, reducing chronic inflammation. FFAR4 also promotes the release of gut hormones like GLP-1, contributing to satiety and glucose homeostasis. Dysregulation of FFAR4 signaling is associated with obesity, insulin resistance, and inflammatory diseases, highlighting its role in metabolic and immune regulation. In cancer, FFAR4 activation has shown potential anti-tumor effects by modulating inflammation and cellular metabolism. FFAR4 is being explored as a therapeutic target for metabolic disorders, obesity, and inflammatory diseases due to its ability to mediate the beneficial effects of omega-3 fatty acids.
Related Products
G Protein Coupled Receptor 120 (GPR120) Antibody
GPR120 Antibody is a Rabbit Polyclonal antibody against GPR120.
Ver Producto
Human G Protein Coupled Receptor 120 / O3FAR1 (FFAR4) ELISA Kit
This product is currently in development. The lead time for this product may be several months. Please contact us at
Ver Producto
Mouse G Protein Coupled Receptor 120 / O3FAR1 (FFAR4) ELISA Kit
Mouse G Protein Coupled Receptor 120 / O3FAR1 (FFAR4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse G Protein Coupled Receptor 120 / O3FAR1 (FFAR4) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of G Protein Coupled Receptor 120 (FFAR4/O3FAR1)
Ver Producto