Follistatin Like Protein 1 (FSTL1) Antibody (FITC)
169€ (20 µg)
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Name
Follistatin Like Protein 1 (FSTL1) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx313312
Description
FSTL1 Antibody (FITC) is a Rabbit Polyclonal against FSTL1 conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Follistatin Like Protein 1 (FSTL1) Immunogen: Recombinant human Follistatin-related protein 1 protein (176-285AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12841 |
| Gene ID | 11167 |
| NCBI Accession | NP_009016.1, NM_007085.4 |
| OMIM | 605547 |
| Alias | FRP,FSL1,OCC1,OCC-1,TSC36,MIR198,Follistatin-related protein 1 |
| Background | Antibody anti-FSTL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Follistatin like 1 (FSTL1) FSTL1 is a secreted glycoprotein that belongs to the SPARC (Secreted Protein Acidic and Rich in Cysteine)-related family and plays diverse roles in development, inflammation, and tissue repair. FSTL1 contains a follistatin-like domain that enables it to interact with various signaling molecules, including members of the TGF-β superfamily. FSTL1 modulates signaling pathways such as BMP (bone morphogenetic protein) signaling, influencing cell differentiation, growth, and immune responses. It is highly expressed in tissues undergoing development or repair, such as the heart, lungs, and skeletal muscles. FSTL1 also exhibits immunomodulatory properties, acting as a pro-inflammatory or anti-inflammatory mediator depending on the context. Dysregulation of FSTL1 has been implicated in inflammatory diseases, cardiovascular conditions, and fibrosis, where it contributes to tissue remodeling and immune dysregulation. In cancer, altered FSTL1 expression can influence tumor progression and metastasis by modulating the tumor microenvironment. Its multifunctional roles in signaling, tissue repair, and immune regulation highlight its potential as a therapeutic target.
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