Folate Receptor Alpha (FOLR1) Antibody

169€ (20 µg)
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name
Folate Receptor Alpha (FOLR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx341886
tested applications
ELISA, IHC, IF/ICC
Description
Folate Receptor Alpha (FOLR1) Antibody is a Rabbit Polyclonal antibody for the detection of Human FOLR1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Folate Receptor Alpha (FOLR1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15328 |
| NCBI Accession | NP_000793.1, NP_057936.1, NP_057937.1, NP_057941.1 |
| Background | Antibody anti-FOLR1 |
| Status | RUO |
Descripción
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FOLR1 antibody
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
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