Flavin Containing Monooxygenase 3 (FMO3) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Flavin Containing Monooxygenase 3 Antibody is a Rabbit Polyclonal antibody against Flavin Containing Monooxygenase 3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Flavin Containing Monooxygenase 3 (FMO3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Ammonium Sulfate Precipitation. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31513 |
| Gene ID | 2328 |
| OMIM | 136132 |
| Background | Antibody anti-FMO3 |
| Status | RUO |
Descripción
Related Products
Dimethylaniline Monooxygenase [N-Oxide-Forming] 3 (FMO3) Antibody
FMO3 Antibody is a Rabbit Polyclonal antibody against FMO3. Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.
Ver Producto
Dimethylaniline Monooxygenase [N-Oxide-Forming] 3 (FMO3) Antibody
FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
Ver Producto
Flavin Containing Monooxygenase 3 (FMO3) Antibody
Flavin Containing Monooxygenase 3 Antibody is a Rabbit Polyclonal antibody against Flavin Containing Monooxygenase 3.
Ver Producto