FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
Primary Antibodies
Polyclonal
Human
Fibroblast Growth Factor Receptor 3 (FGFR3)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
FGFR3
No
Shipped within 5-10 working days.
NP_000133.1, NP_001156685.1, NP_075254.1
This product is for research use only.
Precio a consultar
Ver másPrecio a consultar
Ver másFibroblast Growth Factor Receptor 3 (FGFR3) Antibody is a Rabbit Polyclonal antibody for the detection of FGFR3.
350€ (100 µg)
Ver más