Fibroblast Growth Factor 21 (FGF21) Antibody (FITC)

Este producto es parte de FGF21 - Fibroblast Growth Factor 21
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169€ (20 µg)

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935106861
info@markelab.com
name
Fibroblast Growth Factor 21 (FGF21) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx106836

Description

Fibroblast growth factor 21 Antibody (FITC) is a Rabbit Polyclonal antibody against Fibroblast growth factor 21 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetFibroblast Growth Factor 21 (FGF21)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationFITC
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9NSA1
Gene ID26291
NCBI AccessionNP_061986.1
OMIM609436
AliasFGF-21
BackgroundAntibody anti-FGF21
StatusRUO

Descripción

FGF21 is a metabolic hormone belonging to the fibroblast growth factor family, primarily produced in the liver under conditions of fasting, stress, and ketogenic diet consumption. It regulates glucose metabolism, lipid homeostasis, and energy expenditure by activating FGF receptors in conjunction with the co-receptor β-Klotho. FGF21 enhances insulin sensitivity, promotes lipolysis in adipose tissue, and stimulates ketogenesis in the liver, making it a critical regulator during energy deficits. It has also been linked to reducing body weight and mitigating non-alcoholic fatty liver disease (NAFLD). Therapeutically, FGF21 analogs are being explored for treating type 2 diabetes, obesity, and metabolic disorders. Dysregulation of FGF21 has been observed in insulin resistance and cardiovascular diseases.

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