Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145933
tested applications
ELISA, WB
Description
FCGR3B Antibody is a Rabbit Polyclonal against FCGR3B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC128562 |
| Alias | CD16,FCG3,CD16A,CD16b,FCGR3,CD16-I,FCGR3A,FCR-10,FCRIII,FCRIIIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Fc-gamma RIII-beta,IgG Fc receptor III-1 |
| Background | Antibody anti-FCGR3B |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
FCGR3B, or Fc gamma receptor IIIb, is a low-affinity receptor for the Fc portion of immunoglobulin G (IgG) antibodies, primarily expressed on neutrophils. It is a member of the Fc gamma receptor (FcγR) family, which plays a pivotal role in mediating immune responses through the recognition of the Fc region of IgG antibodies. FCGR3B is one of the two isoforms of FcγRIII, the other being FCGR3A (CD16A). While both isoforms share sequence similarity and belong to the same gene family, they have distinct tissue distributions, membrane anchoring mechanisms, and functional roles in the immune system. FCGR3B is especially important for facilitating immune complex clearance, phagocytosis, and neutrophil activation, processes that are crucial in maintaining immune homeostasis and defending against pathogens. Dysregulation of FCGR3B or mutations in its gene have been associated with a range of clinical conditions, including autoimmune diseases and chronic inflammatory disorders
Related Products
Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Antibody
FCGR3B Antibody is a Rabbit Polyclonal Antibody against FCGR3B.
Ver Producto
Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Protein
Recombinant Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Antibody
Polyclonal Antibody to Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B).
Ver Producto