Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody (PE)

Este producto es parte de FCAR - Fc alpha receptor
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585€ (100 tests)

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935106861
info@markelab.com
name
Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx270988
tested applications
FCM

Description

Fc Fragment Of IgA Receptor (FcaR) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against Fc Fragment Of IgA Receptor (FcaR) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetFc Fragment Of IgA Receptor / CD89 (FCAR)
HostRabbit
ReactivityRat
Recommended DilutionFCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationPE
IsotypeIgG
PurificationPurified by antigen-specific affinity chromatography.
Size 1100 tests
Size 2200 tests
Size 3500 tests
FormLiquid
Tested ApplicationsFCM
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityPlease enquire.
StorageAliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.
Dry IceNo
AliasCD89,FcalphaR,FcalphaRI,CTB-61M7.2,Immunoglobulin alpha Fc receptor, IgA Fc receptor
BackgroundAntibody anti-FCAR
StatusRUO

Descripción

The Fc alpha receptor (FCAR), also known as CD89, is a receptor protein expressed on the surface of certain immune cells, primarily neutrophils, monocytes, macrophages, and some dendritic cells. This receptor binds specifically to the Fc region of immunoglobulin A (IgA), the most abundant antibody found in mucosal secretions and an essential player in immune responses in the gastrointestinal and respiratory tracts. The interaction between CD89 and IgA is critical for initiating immune responses such as phagocytosis, cytokine production, and antibody-dependent cellular cytotoxicity (ADCC). The FCAR gene encoding CD89 is located on chromosome 19q13, and it belongs to the immunoglobulin (Ig) superfamily. The biological significance of CD89 lies in its role as a primary mediator of IgA-dependent immune mechanisms, making it essential in mucosal immunity and in the clearance of pathogens from the body.

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