Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody

Este producto es parte de FCAR - Fc alpha receptor
Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody

Pida mas información

935106861

info@markelab.com

Precio

175€ (20 µl)

Antibody anti-FCAR

proveedor

Abbexa

reference

abx123618

Tested Applications

WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

FCAR Antibody is a Rabbit Polyclonal Antibody against FCAR.


Background

The Fc alpha receptor (FCAR), also known as CD89, is a receptor protein expressed on the surface of certain immune cells, primarily neutrophils, monocytes, macrophages, and some dendritic cells. This receptor binds specifically to the Fc region of immunoglobulin A (IgA), the most abundant antibody found in mucosal secretions and an essential player in immune responses in the gastrointestinal and respiratory tracts. The interaction between CD89 and IgA is critical for initiating immune responses such as phagocytosis, cytokine production, and antibody-dependent cellular cytotoxicity (ADCC). The FCAR gene encoding CD89 is located on chromosome 19q13, and it belongs to the immunoglobulin (Ig) superfamily. The biological significance of CD89 lies in its role as a primary mediator of IgA-dependent immune mechanisms, making it essential in mucosal immunity and in the clearance of pathogens from the body.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Fc Fragment Of IgA Receptor / CD89 (FCAR)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

WB


purification

Purified by affinity chromatography.


buffer

PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.


size 1

20 µl


size 2

50 µl


size 3

100 µl


size 4

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

FCAR


dry ice

No


availability

Shipped within 5-10 working days.


alias

CD89,FcalphaR,FcalphaRI,CTB-61M7.2,Immunoglobulin alpha Fc receptor, IgA Fc receptor


NCBI accession

NP_001991.1


note

This product is for research use only.


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