Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody
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935106861
info@markelab.com
Precio
175€ (20 µl)
Antibody anti-FCAR
proveedor
Abbexareference
abx123618Tested Applications
WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
FCAR Antibody is a Rabbit Polyclonal Antibody against FCAR.
Background
The Fc alpha receptor (FCAR), also known as CD89, is a receptor protein expressed on the surface of certain immune cells, primarily neutrophils, monocytes, macrophages, and some dendritic cells. This receptor binds specifically to the Fc region of immunoglobulin A (IgA), the most abundant antibody found in mucosal secretions and an essential player in immune responses in the gastrointestinal and respiratory tracts. The interaction between CD89 and IgA is critical for initiating immune responses such as phagocytosis, cytokine production, and antibody-dependent cellular cytotoxicity (ADCC). The FCAR gene encoding CD89 is located on chromosome 19q13, and it belongs to the immunoglobulin (Ig) superfamily. The biological significance of CD89 lies in its role as a primary mediator of IgA-dependent immune mechanisms, making it essential in mucosal immunity and in the clearance of pathogens from the body.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Fc Fragment Of IgA Receptor / CD89 (FCAR)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB
purification
Purified by affinity chromatography.
buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
FCAR
dry ice
No
availability
Shipped within 5-10 working days.
alias
CD89,FcalphaR,FcalphaRI,CTB-61M7.2,Immunoglobulin alpha Fc receptor, IgA Fc receptor
uniprot id
NCBI accession
NP_001991.1
note
This product is for research use only.
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