Fas Associated Factor Family Member 2 (FAF2) Antibody
292.5€ (80 µl)
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935106861
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name
Fas Associated Factor Family Member 2 (FAF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030635
tested applications
ELISA, WB
Description
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fas Associated Factor Family Member 2 (FAF2) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96CS3 |
| Background | Antibody anti-FAF2 |
| Status | RUO |
Descripción
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Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).
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