Eukaryotic Translation Initiation Factor 6 (EIF6) Antibody

Eukaryotic Translation Initiation Factor 6 (EIF6) Antibody
312€ (60 µl)

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Name
Eukaryotic Translation Initiation Factor 6 (EIF6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001502
Tested Applications
WB, IF/ICC

Description

EIF6 Antibody is a Rabbit Polyclonal antibody against EIF6. Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Eukaryotic Translation Initiation Factor 6 (EIF6)
Immunogen: Recombinant fusion protein corresponding to human EIF6
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 23 kDa/26 kDa  Observed MW: 27 kDa
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P56537
Gene ID
3692
NCBI Accession
NP_852133.1
Background
Antibody anti-EIF6
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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