Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody
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Description
EIF3C Antibody is a Rabbit Polyclonal against EIF3C.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99613 |
| Gene ID | 8663 |
| NCBI Accession | NP_001032897.1, NM_001037808.2 |
| OMIM | 603916 |
| Background | Antibody anti-EIF3C |
| Status | RUO |
Descripción
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Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody
EIF3C Antibody is a Rabbit Polyclonal antibody against EIF3C.
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Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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