Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody

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Description
EIF3C Antibody is a Rabbit Polyclonal against EIF3C.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/2000 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q99613 |
Gene ID | 8663 |
NCBI Accession | NP_001032897.1, NM_001037808.2 |
OMIM | 603916 |
Background | Antibody anti-EIF3C |
Status | RUO |
Descripción
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Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody
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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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