EIF3C antibody

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935106861
info@markelab.com
name
EIF3C antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02703
tested applications
ELISA, WB, IHC, IF

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
eukaryotic translation initiation factor 3, subunit C (EIF3C)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
105 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
Q99613
Gene ID
8663
Alias
Eukaryotic translation initiation factor 3 subunit C (eIF3c),Eukaryotic translation initiation factor 3 subunit 8,eIF3 p110,EIF3C,EIF3S8
Background
Antibody anti-EIF3C
Status
RUO
Note
Mol. Weight 105 kDa

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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

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