Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Antibody (Biotin)

169€ (20 µg)
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935106861
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name
Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx315694
tested applications
ELISA
Description
EIF2S1 Antibody (Biotin) is a Rabbit Polyclonal against EIF2S1 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Biotin |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P05198 |
Gene ID | 1965 |
OMIM | 603907 |
Background | Antibody anti-EIF2S1 |
Status | RUO |
Descripción
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Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
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