Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody
416€ (200 µl)
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935106861
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name
Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430716
tested applications
P-ELISA, WB, IHC
Description
EEF1E1 Antibody is a Goat Polyclonal antibody against EEF1E1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) |
| Host | Goat |
| Reactivity | Human, Pig |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43324 |
| Gene ID | 9521 |
| NCBI Accession | NP_004271.1, NP_001129122.1 |
| OMIM | 609206 |
| Alias | AIMP3, P18,EEF1E1 |
| Background | Antibody anti-EEF1E1 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
EEF1E1 is a subunit of the eukaryotic elongation factor 1 (eEF1) complex, which plays a critical role in protein synthesis by facilitating the recruitment of aminoacyl-tRNA to the ribosome during elongation. EEF1E1 functions as a structural component, stabilizing the interaction between other subunits, such as EEF1A and EEF1B, within the eEF1 complex. It is also involved in regulating the exchange of GDP for GTP on EEF1A, a critical step in elongation cycle progression. EEF1E1 is expressed ubiquitously, reflecting its essential role in maintaining efficient protein translation in all cells. Dysregulation of EEF1E1 has been linked to cancer progression, where increased protein synthesis supports tumor growth and proliferation. It is also implicated in neurodegenerative diseases, where disruptions in protein homeostasis and elongation factor function are contributing factors. Further studies are needed to explore its broader roles in translational control and disease pathology.
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