Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody

Este producto es parte de EEF1-Eukaryotic Translation Elongation Factor
Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µg)

Antibody anti-EEF1E1

proveedor

Abbexa

reference

abx109285

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Eukaryotic Translation Elongation Factor 1 Epsilon 1 Antibody is a Rabbit Polyclonal antibody against Eukaryotic Translation Elongation Factor 1 Epsilon 1.


Background

EEF1E1 is a subunit of the eukaryotic elongation factor 1 (eEF1) complex, which plays a critical role in protein synthesis by facilitating the recruitment of aminoacyl-tRNA to the ribosome during elongation. EEF1E1 functions as a structural component, stabilizing the interaction between other subunits, such as EEF1A and EEF1B, within the eEF1 complex. It is also involved in regulating the exchange of GDP for GTP on EEF1A, a critical step in elongation cycle progression. EEF1E1 is expressed ubiquitously, reflecting its essential role in maintaining efficient protein translation in all cells. Dysregulation of EEF1E1 has been linked to cancer progression, where increased protein synthesis supports tumor growth and proliferation. It is also implicated in neurodegenerative diseases, where disruptions in protein homeostasis and elongation factor function are contributing factors. Further studies are needed to explore its broader roles in translational control and disease pathology.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC, IF/ICC


purity

> 95%


purification

Purified by Protein G.


recommended dilution

WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

EEF1E1


dry ice

No


availability

Shipped within 5-10 working days.


alias

AIMP3, P18,EEF1E1


NCBI accession

NP_001129122.1, NM_001135650.1


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