Estrogen-Related Receptor Gamma (ESRRG) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Estrogen-Related Receptor Gamma (ESRRG) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122813
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ESRRG protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Estrogen-Related Receptor Gamma (ESRRG) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC064700 |
| Alias | ERR3,ERRg,NR3B3,ERRgamma2,Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3 |
| Background | Antibody anti-ESRRG |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Estrogen related receptor gamma (ESRRG), also known as ERRγ, is a nuclear receptor that regulates a wide range of biological processes, including mitochondrial function, energy metabolism, and cellular differentiation ESRRG is expressed in various tissues, including the heart, brain, and skeletal muscle, where it helps control the transcription of genes involved in oxidative phosphorylation and mitochondrial biogenesis It plays a central role in maintaining cellular energy balance by regulating the expression of genes involved in energy production and metabolism In addition to its metabolic roles, ESRRG is involved in regulating the development of the cardiovascular system, the central nervous system, and adipose tissue Dysregulation of ESRRG has been linked to metabolic diseases, including obesity, diabetes, and cardiovascular diseases, as well as certain cancers, where altered mitochondrial function contributes to tumorigenesis ESRRG’s role in regulating energy metabolism and mitochondrial function makes it an important target for therapeutic strategies aimed at treating metabolic and cardiovascular diseases as well as improving mitochondrial health
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