anti- ESRRG antibody
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935106861
info@markelab.com
name
anti- ESRRG antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02872
tested applications
ELISA, WB
Description
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements(By similarity). Induces the expression of PERM1 in the skeletal muscle.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | estrogen-related receptor gamma |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500 - 1:3000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 51 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P62508 |
| Gene ID | 2104 |
| Alias | ERR3,ERRg,NR3B3,ERRgamma2,Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3 |
| Background | Antibody anti-ESRRG |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
Estrogen related receptor gamma (ESRRG), also known as ERRγ, is a nuclear receptor that regulates a wide range of biological processes, including mitochondrial function, energy metabolism, and cellular differentiation ESRRG is expressed in various tissues, including the heart, brain, and skeletal muscle, where it helps control the transcription of genes involved in oxidative phosphorylation and mitochondrial biogenesis It plays a central role in maintaining cellular energy balance by regulating the expression of genes involved in energy production and metabolism In addition to its metabolic roles, ESRRG is involved in regulating the development of the cardiovascular system, the central nervous system, and adipose tissue Dysregulation of ESRRG has been linked to metabolic diseases, including obesity, diabetes, and cardiovascular diseases, as well as certain cancers, where altered mitochondrial function contributes to tumorigenesis ESRRG’s role in regulating energy metabolism and mitochondrial function makes it an important target for therapeutic strategies aimed at treating metabolic and cardiovascular diseases as well as improving mitochondrial health
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anti- ESRRG antibody
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements(By similarity). Induces the expression of PERM1 in the skeletal muscle.
Ver Producto