ESPL1 (pS1126) Antibody

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208€ (20 µl)

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935106861
info@markelab.com
name
ESPL1 (pS1126) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000516
tested applications
ELISA, WB

Description

ESPL1 (pS1126) Antibody is a Rabbit Polyclonal antibody against ESPL1 (pS1126). Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ESPL1 (pS1126)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q14674
Gene ID
9700
NCBI Accession
NP_036423.4
Background
Antibody anti-ESPL1
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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abx000516

ESPL1 (pS1126) Antibody

ESPL1 (pS1126) Antibody is a Rabbit Polyclonal antibody against ESPL1 (pS1126). Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids.

Ver Producto