Escherichia coli Lipopolysaccharide (LPS) Antibody Pair
1482€ (5 × 96 tests)
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name
Escherichia coli Lipopolysaccharide (LPS) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370829
tested applications
ELISA
Description
Lipopolysaccharide (LPS) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Detection: 50 µg Capture: 200 µg Standard: 0.5 µg
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Escherichia coli Lipopolysaccharide (LPS) |
| Host | Capture Host: Mouse Detection Host: Mouse |
| Reactivity | General |
| Assay Data | Sandwich |
| Assay Type | Capture Antibody: 0.5 mg/ml Biotin-Conjugated Detection Antibody: 0.2 mg/ml Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
| Test Range | 0.47 ng/ml - 30 ng/ml |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Capture Clonality: Monoclonal Detection Clonality: Monoclonal |
| Conjugation | Biotin |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard form: Lyophilized Capture Ab: Liquid Detection Ab: Liquid |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.05% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | LPS |
| Background | Antibody pair for LPS |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Lipopolysaccharides (LPS) are large molecules found in the outer membrane of Gram-negative bacteria, playing a crucial role in the structural integrity of bacterial cells and acting as a potent activator of the immune system. Composed of lipid A, a core oligosaccharide, and an O-antigen polysaccharide, LPS is a critical factor in bacterial pathogenicity. Lipid A is the bioactive component that triggers immune responses by binding to the Toll-like receptor 4 (TLR4) complex on immune cells, leading to the activation of nuclear factor-kappa B (NF-κB) and the release of pro-inflammatory cytokines such as IL-6 and TNF-alpha. While LPS is essential for host defense, its excessive activation can result in septic shock, characterized by systemic inflammation, organ failure, and high mortality. Therapeutic strategies targeting LPS-TLR4 signaling pathways are being explored to manage sepsis and other inflammatory conditions.
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