Mitogen-Activated Protein Kinase 1 Phospho-Thr185/Tyr187 and 3 Phospho-Thr202/Tyr204 (MAPK1 pT185/Y187/MAPK3 pT202/Y204) Antibody
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Description
Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody is a Rabbit Polyclonal antibody against Erk1 (pT202/Y204) / Erk2 (pT185/Y187). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitogen-Activated Protein Kinase 1 Phospho-Thr185/Tyr187 and 3 Phospho-Thr202/Tyr204 (MAPK1 pT185/Y187 / MAPK3 pT202/Y204) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28482, P27361 |
| Gene ID | 5594/5595 |
| NCBI Accession | NP_002736.3 |
| Background | Antibody anti-MAPK1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Mitogen-Activated Protein Kinase 1 Phospho-Thr185/Tyr187 and 3 Phospho-Thr202/Tyr204 (MAPK1 pT185/Y187/MAPK3 pT202/Y204) Antibody
Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody is a Rabbit Polyclonal antibody against Erk1 (pT202/Y204) / Erk2 (pT185/Y187). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Ver Producto