ERCC2 antibody
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P18074 |
| Alias | General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD),Basic transcription factor 2 80 kDa subunit (BTF2 p80),CXPD,DNA excision repair protein ERCC-2,DNA repair protein complementing XP-D cells,TFIIH basal transcription factor complex 80 kDa subunit (TFIIH 80 kDa subunit, TFIIH p80),Xeroderma pigmentosum group D-complementing protein,ERCC2,XPD,XPDC |
| Background | Antibody anti-ERCC2 |
| Status | RUO |
| Note | Mol. Weight 80 kDa |
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ERCC2 antibody
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
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General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2) Antibody
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