Epidermal Growth Factor 21-Leu Protein

234€ (20 µg)
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935106861
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name
Epidermal Growth Factor 21-Leu Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263115
tested applications
SDS-PAGE
Description
Epidermal Growth Factor 21-Leu Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | EGF (Leu 21) |
Origin | Human |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 98% (SDS-PAGE and RP-HPLC) |
Size 1 | 20 µg |
Size 2 | 100 µg |
Size 3 | 1 mg |
Form | Lyophilized |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
Alias | FGF-21 |
Background | Protein FGF21 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
FGF21 is a metabolic hormone belonging to the fibroblast growth factor family, primarily produced in the liver under conditions of fasting, stress, and ketogenic diet consumption. It regulates glucose metabolism, lipid homeostasis, and energy expenditure by activating FGF receptors in conjunction with the co-receptor β-Klotho. FGF21 enhances insulin sensitivity, promotes lipolysis in adipose tissue, and stimulates ketogenesis in the liver, making it a critical regulator during energy deficits. It has also been linked to reducing body weight and mitigating non-alcoholic fatty liver disease (NAFLD). Therapeutically, FGF21 analogs are being explored for treating type 2 diabetes, obesity, and metabolic disorders. Dysregulation of FGF21 has been observed in insulin resistance and cardiovascular diseases.
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