Ephexin-1 (NGEF) Antibody (FITC)
260€ (50 µl)
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935106861
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name
Ephexin-1 (NGEF) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx348501
Description
Ephexin-1 (NGEF) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human NGEF.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ephexin-1 (NGEF) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N5V2 |
| Gene ID | 25791 |
| OMIM | 605991 |
| Background | Antibody anti-NGEF |
| Status | RUO |
Descripción
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NGEF antibody
Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
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Ephexin-1 (NGEF) Antibody
Ephexin-1 (NGEF) Antibody is a Rabbit Polyclonal antibody for the detection of Human NGEF.
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