EPH Receptor A4 (EphB4) Antibody
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Description
EphB4: EPH receptor B4.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | EPH Receptor A4 (EphB4) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P54760 |
| Gene ID | 2050 |
| OMIM | 600011 |
| Background | Antibody anti-EphB4 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
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EPH Receptor A4 (EphB4) Antibody
EphB4: EPH receptor B4.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
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