Endothelin 1 (EDN1) Antibody
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935106861
info@markelab.com
Precio
250€ (50 µl)
Antibody anti-EDN1
proveedor
Abbexareference
abx210817Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
EDN1 Antibody is a Rabbit Polyclonal against EDN1.
Background
Endothelin-1 (EDN1) is a peptide hormone belonging to the endothelin family. It plays a crucial role in regulating blood vessel contraction and dilation, thereby influencing blood pressure and blood flow throughout the body. Endothelin-1 is primarily produced by endothelial cells, It is also produced by other cell types, including vascular smooth muscle cells, cardiomyocytes, and certain inflammatory cells.Endothelin-1 acts as a potent vasoconstrictor, meaning it causes blood vessels to narrow, leading to an increase in blood pressure. Dysregulation of endothelin-1 signaling is associated with several cardiovascular disorders, including hypertension, atherosclerosis, coronary artery disease, and pulmonary hypertension. Elevated levels of endothelin-1 have been observed in individuals with these conditions, contributing to their pathogenesis. Endothelin-1 is able to bind to specific receptors on target cells known as endothelin receptors. There are two main types of endothelin receptors: endothelin receptor type A (ETA) and endothelin receptor type B (ETB).
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Endothelin 1 (EDN1)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purification
Antigen Affinity Chromatography.
buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
EDN1
dry ice
No
availability
Shipped within 5-10 working days.
alias
ARCND3,ET1, ET-1,HDLCQ7,QME,PPET1
uniprot id
note
This product is for research use only.
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