Embigin (EMB) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Embigin (EMB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx125809
tested applications
ELISA, WB
Description
EMB Antibody is a Rabbit Polyclonal against EMB.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Embigin (EMB) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6PCB8 |
| Gene ID | 133418 |
| NCBI Accession | NP_940851.1 |
| Alias | GP70 |
| Background | Antibody anti-EMB |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Embigin (EMB) Embigin is a transmembrane glycoprotein belonging to the immunoglobulin superfamily, primarily involved in cell adhesion and signaling. It is expressed in a variety of tissues, including developing muscle and epithelial cells, where it contributes to cellular interactions with the extracellular matrix (ECM). Embigin interacts with components of the ECM, such as integrins and laminins, to modulate processes like cell migration, differentiation, and tissue morphogenesis. Additionally, embigin has been implicated in metabolic regulation by influencing monocarboxylate transporters (MCTs), which are critical for lactate and pyruvate transport in metabolic tissues. Its expression is dynamically regulated during development and in response to cellular stress, with aberrant levels linked to cancer progression and metastasis, where it may enhance tumor cell invasion through ECM remodeling. Structurally, embigin contains immunoglobulin-like domains that facilitate its interactions with cellular and ECM components, highlighting its role as a mediator of cellular and environmental communication.
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