EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) Antibody (PE)
234€ (25 tests)
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935106861
info@markelab.com
name
EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx414983
tested applications
IF/ICC, FCM
Description
EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) Antibody (PE) is a Rat Monoclonal antibody against F4/80.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) |
| Host | Rat |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2b |
| Purification | Purified |
| Size 1 | 25 tests |
| Size 2 | 100 tests |
| Form | Lyophilized |
| Tested Applications | IF/ICC, FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at -20 °C or -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q61549 |
| Alias | ADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3 |
| Background | Antibody anti-ADGRE1 |
| Status | RUO |
Descripción
ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.
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