EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (Eltd1) Antibody
273€ (200 µl)
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935106861
info@markelab.com
name
EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (Eltd1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432647
tested applications
P-ELISA
Description
Eltd1 Antibody is a Goat Polyclonal antibody against Eltd1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (Eltd1) |
| Host | Goat |
| Reactivity | Zebrafish |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_998532.1 |
| Alias | ADGRL4,ETL,EGF-TM7-latrophilin-related protein,ELTD1 |
| Background | Antibody anti-ADGRL4 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
ADGRL4, formerly known as ELTD1 (EGF, Latrophilin, and Seven-Transmembrane Domain-Containing Protein 1), is expressed in vascular endothelial cells and plays an essential role in vascular remodeling, angiogenesis, and endothelial cell migration. By interacting with extracellular matrix components and signaling proteins, ADGRL4 influences cellular communication, proliferation, and the structural organization of blood vessels. It has been extensively studied for its involvement in tumor angiogenesis, where its overexpression correlates with aggressive cancer progression and poor prognosis. Beyond its role in pathological angiogenesis, ADGRL4 is critical for maintaining vascular stability and endothelial barrier function under normal physiological conditions. Dysregulation of ADGRL4 is associated with pathological vascular remodeling and cardiovascular diseases, emphasizing its potential as a therapeutic target in oncology and vascular medicine. Its multifunctional nature makes it a key player in both physiological vascular processes and disease states.
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