EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (ELTD1) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (ELTD1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx249473
tested applications
IF/ICC
Description
ELTD1 Antibody is a Rabbit Polyclonal against ELTD1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | EGF, Latrophilin And Seven Transmembrane Domain-Containing Protein 1 (ELTD1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBW9 |
| Alias | ADGRL4,ETL,EGF-TM7-latrophilin-related protein,ELTD1 |
| Background | Antibody anti-ADGRL4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ADGRL4, formerly known as ELTD1 (EGF, Latrophilin, and Seven-Transmembrane Domain-Containing Protein 1), is expressed in vascular endothelial cells and plays an essential role in vascular remodeling, angiogenesis, and endothelial cell migration. By interacting with extracellular matrix components and signaling proteins, ADGRL4 influences cellular communication, proliferation, and the structural organization of blood vessels. It has been extensively studied for its involvement in tumor angiogenesis, where its overexpression correlates with aggressive cancer progression and poor prognosis. Beyond its role in pathological angiogenesis, ADGRL4 is critical for maintaining vascular stability and endothelial barrier function under normal physiological conditions. Dysregulation of ADGRL4 is associated with pathological vascular remodeling and cardiovascular diseases, emphasizing its potential as a therapeutic target in oncology and vascular medicine. Its multifunctional nature makes it a key player in both physiological vascular processes and disease states.
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