Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) Antibody (FITC)
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Description
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) Antibody (FITC) is a FITC-conjugated Mouse Monoclonal antibody for Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 4 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Clone ID | G671 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C in the dark. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P49961 |
| Gene ID | 953 |
| Alias | CD39,SPG64,ATP-DPH,ATPDase,NTPDase-1,ATP diphosphohydrolase,Ecto-ATP diphosphohydrolase 1,Ecto-apyrase,Lymphoid cell activation antigen ,Nucleoside triphosphate diphosphohydrolase 1 |
| Background | Antibody anti-ENTPD1 |
| Status | RUO |
Descripción
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Human ENTPD1 (Ectonucleoside triphosphate diphosphohydrolase 1) ELISA Kit
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ENTPD1 antibody
ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.
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In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
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