Ecto-ADP-Ribosyltransferase 4 (ART4) Antibody

Este producto es parte de ART4 - ADP-ribosyltransferase 4
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221€ (50 µg)

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935106861
info@markelab.com
name
Ecto-ADP-Ribosyltransferase 4 (ART4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx323205
tested applications
ELISA, IHC

Description

ART4 Antibody is a Rabbit Polyclonal against ART4.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Ecto-ADP-Ribosyltransferase 4 (ART4)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/10000 - 1/20000, IHC: 1/50 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q93070
Gene ID
420
Alias
ADP-ribosyltransferase C2 and C3 toxin-like 4,Dombrock blood group,DO,DOK1,ARTC4,CD297,DO/ART4,Ecto-ADP-ribosyltransferase 4,Mono(ADP-ribosyl)transferase 4
Background
Antibody anti-ART4
Status
RUO

Descripción

ADP-ribosyltransferase 4 (ART4), also known as CD297, is an enzyme that belongs to the ART family of ADP-ribosyltransferases. These enzymes mediate the transfer of ADP-ribose from NAD+ (nicotinamide adenine dinucleotide) to specific target proteins, a modification that alters their functions. ADP-ribosylation is a post-translational modification that can impact a variety of cellular processes, such as signaling, immune regulation, and cell differentiation. ART4 is a GPI-anchored ectoenzyme, meaning it is attached to the outer surface of the plasma membrane and targets extracellular proteins. ART4 is particularly known for its association with the Dombrock (Do) blood group system, where variations in ART4 contribute to antigenic diversity on red blood cells. Its functions and expression are implicated in immune cell regulation, and it has been investigated for potential roles in immune and hematologic disorders.

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