E3 Ubiquitin-Protein Ligase TRIM37 (TRIM37) Antibody

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Description
Tripartite Motif-Containing 37 Antibody is a Rabbit Polyclonal antibody against Tripartite Motif-Containing 37.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | E3 Ubiquitin-Protein Ligase TRIM37 (TRIM37) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O94972 |
| Gene ID | 4591 |
| NCBI Accession | NP_001005207.1, NM_001005207.3 |
| OMIM | 253250 |
| Background | Antibody anti-TRIM37 |
| Status | RUO |
Descripción
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TRIM37 antibody
E3 ubiquitin-protein ligase required to prevent centriole reduplication(PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication(PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group(PcG) multiprotein PRC2-like complex and mediates repression of target genes(PubMed:25470042). Has anti-HIV activity(PubMed:24317724).
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TRIM37 Antibody is a Rabbit Polyclonal against TRIM37.
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