E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP)
260€ (50 µl)
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935106861
info@markelab.com
name
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx344960
tested applications
ELISA
Description
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human MDM2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | E3 ubiquitin-protein ligase Mdm2 (MDM2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q00987 |
| Gene ID | 4193 |
| OMIM | 164785 |
| Background | Antibody anti-MDM2 |
| Status | RUO |
Descripción
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MDM2 antibody
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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