anti- MDM2 antibody

Name: anti- MDM2 antibody
Brand: FineTest
SKU: FNab05077
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-MDM2

proveedor

FineTest

reference

FNab05077

Tested Applications

ELISA, IHC, WB, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

Mdm2 p53 binding protein homolog ( Mouse )

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IHC, WB, IF

observerd MW

50 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

or code

MDM2

alias

ACTFS

uniprot id

https://www.uniprot.org/uniprotkb/Q00987

gene id

https://www.ncbi.nlm.nih.gov/gene/4193

note

This product is for research use only.

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