Dual Specificity Phosphatase 8 (DUSP8) Antibody

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Description
DUSP8 Antibody is a Rabbit Polyclonal against DUSP8.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Dual Specificity Phosphatase 8 (DUSP8) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q13202 |
Gene ID | 1850 |
Background | Antibody anti-DUSP8 |
Status | RUO |
Descripción
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Dual Specificity Phosphatase 8 (DUSP8) Antibody
DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.
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Dual Specificity Phosphatase 8 (DUSP8) Antibody
DUSP8 Antibody is a Rabbit Polyclonal against DUSP8.
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Dual Specificity Phosphatase 8 (DUSP8) Antibody
DUSP8 Antibody is a Rabbit Polyclonal against DUSP8.
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