Dual Specificity Phosphatase 6 (DUSP6) Antibody
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Description
Rabbit polyclonal antibody against DUSP6 protein. Immunogen region is Internal.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Dual Specificity Phosphatase 6 (DUSP6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16828 |
| Gene ID | 1848 |
| Background | Antibody anti-DUSP6 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Dual Specificity Phosphatase 6 (DUSP6) Antibody
DUSP6 Antibody is a Rabbit Polyclonal antibody against DUSP6. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
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Dual Specificity Phosphatase 6 (DUSP6) Antibody
Rabbit polyclonal antibody against DUSP6 protein. Immunogen region is Internal.
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