Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005276
tested applications
IHC, IF/ICC

Description

MAP2K5 Antibody is a Rabbit Polyclonal antibody against MAP2K5. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13163
Gene ID
5607
NCBI Accession
NP_660143.1
Background
Antibody anti-MAP2K5
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

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MAP2K5 Antibody is a Rabbit Polyclonal antibody against MAP2K5. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

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