Down Syndrome Critical Region Protein 1 (DSCR1) Antibody

Name: Down Syndrome Critical Region Protein 1 (DSCR1) Antibody
Brand: Abbexa
SKU: abx025111
Price: 292.5 EUR
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-DSCR1

proveedor

Abbexa

reference

abx025111

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Down Syndrome Critical Region Protein 1 (DSCR1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

recommended dilution

WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

DSCR1

dry ice

availability

Shipped within 5-10 working days.

uniprot id

https://www.uniprot.org/uniprotkb/P53805

NCBI accession

NP_004405.3, NP_981962.1, NP_981963.1

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