Docking Protein 4 (DOK4) Antibody

Name: Docking Protein 4 (DOK4) Antibody
Brand: Abbexa
SKU: abx326161
Price: 221 EUR
Availability: OnlineOnly

Este producto es parte de DOK - Docking protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (50 µg)

Antibody anti-DOK4

proveedor

Abbexa

reference

abx326161

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

DOK4 Antibody is a Rabbit Polyclonal against DOK4.

Background

DOK4 is an adaptor protein belonging to the DOK family, involved in signal transduction downstream of receptor tyrosine kinases, such as RET and insulin receptors. It modulates pathways like MAPK/ERK and PI3K/Akt, influencing cellular proliferation, survival, and differentiation. DOK4 is expressed in tissues like skeletal muscle, adipose tissue, and the nervous system, where it regulates metabolic signaling and cellular responses. It acts as a negative regulator of signaling by binding to SH2 domains and inhibiting downstream activation. Dysregulation of DOK4 is associated with metabolic disorders, insulin resistance, and certain cancers, where it influences cell adhesion and motility.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Docking Protein 4 (DOK4)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC, IF/ICC

purification

Purified by affinity chromatography.

recommended dilution

ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

size 1

50 µg

size 2

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

DOK4

dry ice

availability

Shipped within 5-10 working days.

alias

Downstream of tyrosine kinase 4,Insulin receptor substrate 5,IRS-5,IRS5

uniprot id

https://www.uniprot.org/uniprotkb/Q8TEW6

gene id

https://www.ncbi.nlm.nih.gov/gene/55715

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anti- DOK4 antibody

proveedor

FineTest

reference

FNab02503

Tested Applications

ELISA, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly o...

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