DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody
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Description
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody is a Rabbit Polyclonal antibody against DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L). This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P62876 |
| Gene ID | 66491 |
| NCBI Accession | NP_066951.1 |
| Background | Antibody anti-POLR2L |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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POLR2L antibody
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft(By similarity).
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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody is a Rabbit Polyclonal antibody against DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L). This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Ver Producto
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody
DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L) Antibody is a Rabbit Polyclonal antibody against DNA-Directed RNA Polymerases I, II, And III Subunit RPABC5 (POLR2L). This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008].
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