DNA-Directed RNA Polymerase III Subunit RPC9 (CRCP) Antibody

312€ (60 µl)
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935106861
info@markelab.com
name
DNA-Directed RNA Polymerase III Subunit RPC9 (CRCP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx003510
tested applications
WB
Description
CRCP Antibody is a Rabbit Polyclonal antibody against CRCP. This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | DNA-Directed RNA Polymerase III Subunit RPC9 (CRCP) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O75575 |
Gene ID | 27297 |
NCBI Accession | NP_001035737.1 |
Background | Antibody anti-CRCP |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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CRCP antibody
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
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