CRCP antibody
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935106861
info@markelab.com
name
CRCP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01955
tested applications
ELISA, WB, IHC, FC, IP
Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CGRP receptor component (CRCP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 20 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, FC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O75575 |
| Gene ID | 27297 |
| Alias | DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9),Calcitonin gene-related peptide-receptor component protein (CGRP-RCP, CGRP-receptor component protein, CGRPRCP, HsC17),CRCP |
| Background | Antibody anti-CRCP |
| Status | RUO |
| Note | Mol. Weight 20 kDa |
Descripción
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CRCP antibody
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
Ver Producto