DNA damage-inducible transcript 3 protein (DDIT3) Antibody
299€ (50 µl)
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935106861
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name
DNA damage-inducible transcript 3 protein (DDIT3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402487
tested applications
ELISA, FCM
Description
DNA damage-inducible transcript 3 protein (DDIT3) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human DDIT3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA damage-inducible transcript 3 protein (DDIT3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35638 |
| Gene ID | 1649 |
| OMIM | 126337 |
| Background | Antibody anti-DDIT3 |
| Status | RUO |
Descripción
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CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
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