DDIT3 antibody

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935106861
info@markelab.com
name
DDIT3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01667
tested applications
ELISA, IHC, WB
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | DNA-damage-inducible transcript 3 (DDIT3) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 30 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P35638 |
Gene ID | 1649 |
Alias | DNA damage-inducible transcript 3 protein (DDIT-3),C/EBP zeta,C/EBP-homologous protein (CHOP),C/EBP-homologous protein 10 (CHOP-10),CCAAT/enhancer-binding protein homologous protein,Growth arrest and DNA damage-inducible protein GADD153,DDIT3,CHOP,CHOP10,GADD153 |
Background | Antibody anti-DDIT3 |
Status | RUO |
Note | Mol. Weight 30 kDa |
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CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
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