DNA-binding protein RFXANK (RFXANK) Antibody (Biotin)
169€ (20 µg)
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935106861
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name
DNA-binding protein RFXANK (RFXANK) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx335432
tested applications
ELISA
Description
RFXANK Antibody (Biotin) is a Rabbit Polyclonal against RFXANK.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA-binding protein RFXANK (RFXANK) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14593 |
| Gene ID | 8625 |
| Alias | Ankyrin repeat family A protein 1,RFXB,RFXANK |
| Background | Antibody anti-ANKRA1 |
| Status | RUO |
Descripción
ANKRA1 is a protein that contains ankyrin repeat domains, which are known for mediating protein-protein interactions. ANKRA1 is involved in cellular processes such as transcriptional regulation, signal transduction, and chromatin remodeling by serving as an adaptor protein that links different protein complexes. ANKRA1 has been identified as an interactor with histone deacetylases (HDACs), suggesting its role in modulating gene expression through chromatin structure alteration. This interaction allows ANKRA1 to participate in transcriptional repression and epigenetic regulation of gene activity. ANKRA1 is also implicated in cellular differentiation and immune signaling pathways, particularly in the regulation of inflammatory responses. Dysregulation of ANKRA1 expression has been linked to cancer progression and aberrant cell growth, where it may influence pathways involved in proliferation and survival. Its function as a scaffold protein highlights its significance in coordinating multiprotein complexes to maintain gene expression and cellular homeostasis.
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