Disintegrin And Metalloproteinase Domain-Containing Protein 23 (ADAM23) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Disintegrin And Metalloproteinase Domain-Containing Protein 23 (ADAM23) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx341196
tested applications
ELISA, WB, IHC, IF/ICC
Description
Disintegrin And Metalloproteinase Domain-Containing Protein 23 (ADAM23) Antibody is a Rabbit Polyclonal antibody for the detection of Human ADAM23.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Disintegrin And Metalloproteinase Domain-Containing Protein 23 (ADAM23) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75077 |
| Alias | MDC3,A Disintegrin And Metalloproteinase Domain 23,adam-23 |
| Background | Antibody anti-ADAM23 |
| Status | RUO |
Descripción
ADAM23 (A Disintegrin And Metalloproteinase domain-containing protein 23) is a member of the ADAM family of proteins, which are transmembrane proteins with diverse functions including cell adhesion, migration, proteolysis, and signaling. The ADAM family is characterized by the presence of a conserved metalloproteinase domain, which is responsible for their proteolytic activity, as well as other functional domains such as disintegrin, cysteine-rich, transmembrane, and cytoplasmic domains. ADAM23 specifically is known to play roles in neuronal development and function. It is predominantly expressed in the nervous system, particularly in the brain, including regions such as the cerebellum, cerebral cortex, hippocampus, and olfactory bulb. Within these regions, ADAM23 is involved in processes such as neurite outgrowth, axon guidance, synaptogenesis, and synaptic plasticity. ADAM23 may function as a receptor for various extracellular matrix proteins and cell adhesion molecules, allowing it to mediate interactions between neurons and their surrounding environment. Additionally, ADAM23 has been implicated in neurodevelopmental disorders and neurological diseases, although the precise mechanisms are not fully understood.
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