DIS3-Like Exonuclease 1 (DIS3L) Antibody

Name: DIS3-Like Exonuclease 1 (DIS3L) Antibody
Brand: Abbexa
SKU: abx232395
Price: 364 EUR
Availability: OnlineOnly

364€ (100 µg)

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DIS3-Like Exonuclease 1 (DIS3L) Antibody

Description

DIS3L Antibody is a Rabbit Polyclonal against DIS3L.

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Product specifications

Category	Primary Antibodies
Immunogen Target	DIS3-Like Exonuclease 1 (DIS3L)
Host	Rabbit
Reactivity	Human
Recommended Dilution	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality	Polyclonal
Conjugation	Unconjugated
Isotype	IgG
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Size 1	100 µg
Form	Liquid
Tested Applications	ELISA, WB
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-12 working days.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice	No
UniProt ID	Q8TF46
Gene ID	115752
OMIM	614183
Background	Antibody anti-DIS3L
Status	RUO
Note	Concentration: 2 mg/ml - Validity: 12 months.

Descripción

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DIS3L antibody

Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

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